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Uncertainty-aware Diffusion and Reinforcement Learning for Joint Plane Localization and Anomaly Diagnosis in 3D Ultrasound

Created by
  • Haebom

Author

Yuhao Huang, Yueyue Xu, Haoran Dou, Jiaxiao Deng, Xin Yang, Hongyu Zheng, Dong Ni

Outline

Congenital uterine anomalies (CUAs) can cause infertility, miscarriage, premature birth, and an increased risk of pregnancy complications. Compared to conventional 2D ultrasound (US), 3D US can accurately assess CUA by reconstructing the coronal plane and clearly visualizing the uterine morphology. In this paper, we propose an intelligent system that simultaneously automates plane localization and CUA diagnosis in uterine ultrasound images. Key findings include: 1) We develop a denoising diffusion model using local (planar) and global (volume/text) guidance, employing an adaptive weighting strategy to optimize attention across various conditions. 2) We introduce a reinforcement learning-based framework using unsupervised rewards to extract key slice summaries from redundant sequences and fully integrate information from multiple planes, reducing learning difficulty. 3) We use text-based uncertainty modeling to provide crude predictions and adjust classification probabilities to improve overall performance. Extensive experiments on a large-scale 3D uterine ultrasound dataset demonstrate the effectiveness of the proposed method in plane localization and CUA diagnosis. The code is available at https://github.com/yuhoo0302/CUA-US .

Takeaways, Limitations

Takeaways:
Improving the accuracy of diagnosing congenital uterine anomalies (CUAs) using 3D uterine ultrasound imaging.
Increasing diagnostic efficiency through the development of an automated plane positioning and CUA diagnostic system.
Effective integration of various deep learning techniques, including noise-removing diffusion models, reinforcement learning, and text-based uncertainty modeling.
Performance verification through experiments using large-scale datasets.
Reproducibility and further research are possible through open code.
Limitations:
Further research is needed to evaluate the generalizability of the proposed method. The impact of various uterine morphologies and ultrasound devices should also be evaluated.
Analysis is needed to determine how dataset bias may affect the results.
Further research is needed to validate clinical efficacy. Performance evaluation in real-world clinical settings and incorporating feedback from medical professionals are essential.
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