Daily Arxiv

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JWB-DH-V1: Benchmark for Joint Whole-Body Talking Avatar and Speech Generation Version 1

T2I-Copilot: A Training-Free Multi-Agent Text-to-Image System for Enhanced Prompt Interpretation and Interactive Generation

The Xeno Sutra: Can Meaning and Value be Ascribed to an AI-Generated "Sacred" Text?

Humanoid Occupancy: Enabling A Generalized Multimodal Occupancy Perception System on Humanoid Robots

Sem-DPO: Mitigating Semantic Inconsistency in Preference Optimization for Prompt Engineering

The Carbon Cost of Conversation, Sustainability in the Age of Language Models

Machine Learning Risk Intelligence for Green Hydrogen Investment: Insights for Duqm R3 Auction

Differential-UMamba: Rethinking Tumor Segmentation Under Limited Data Scenarios

Decoding Instructional Dialogue: Human-AI Collaborative Analysis of Teacher Use of AI Tool at Scale

Towards Facilitated Fairness Assessment of AI-based Skin Lesion Classifiers Through GenAI-based Image Synthesis

Reinforcement Learning Fine-Tunes a Sparse Subnetwork in Large Language Models

Machine learning-based multimodal prognostic models integrating pathology images and high-throughput omic data for overall survival prediction in cancer: a systematic review

Diffusion Beats Autoregressive in Data-Constrained Settings

SegQuant: A Semantics-Aware and Generalizable Quantization Framework for Diffusion Models

Linguistic and Embedding-Based Profiling of Texts generated by Humans and Large Language Models

AI-ming backwards: Vanishing archaeological landscapes in Mesopotamia and automatic detection of sites on CORONA imagery

Kodezi Chronos: A Debugging-First Language Model for Repository-Scale Code Understanding

TolerantECG: A Foundation Model for Imperfect Electrocardiogram

AMix-1: A Pathway to Test-Time Scalable Protein Foundation Model

Audio Flamingo 3: Advancing Audio Intelligence with Fully Open Large Audio Language Models

HIRAG: Hierarchical-Thought Instruction-Tuning Retrieval-Augmented Generation

ZERO: Industry-ready Vision Foundation Model with Multi-modal Prompts

End-to-End Large Portfolio Optimization for Variance Minimization with Neural Networks through Covariance Cleaning

iPanda: An LLM-based Agent for Automated Conformance Testing of Communication Protocols

SurgiSR4K: A High-Resolution Endoscopic Video Dataset for Robotic-Assisted Minimally Invasive Procedures

Generating Heterogeneous Multi-dimensional Data : A Comparative Study

Automated Generation of Diverse Courses of Actions for Multi-Agent Operations using Binary Optimization and Graph Learning

GLIMPSE: Holistic Cross-Modal Explainability for Large Vision-Language Models

Fine-Grained Perturbation Guidance via Attention Head Selection

FlagEvalMM: A Flexible Framework for Comprehensive Multimodal Model Evaluation

SmoothRot: Combining Channel-Wise Scaling and Rotation for Quantization-Friendly LLMs

LinkTo-Anime: A 2D Animation Optical Flow Dataset from 3D Model Rendering

Incentivizing Reasoning for Advanced Instruction-Following of Large Language Models

Adversarial bandit optimization for approximately linear functions

FB-RAG: Improving RAG with Forward and Backward Lookup

Mining Intrinsic Rewards from LLM Hidden States for Efficient Best-of-N Sampling

Learning Pareto-Optimal Rewards from Noisy Preferences: A Framework for Multi-Objective Inverse Reinforcement Learning

Context-Aware Probabilistic Modeling with LLM for Multimodal Time Series Forecasting

Multi-Modal Hypergraph Enhanced LLM Learning for Recommendation

OPAL: Encoding Causal Understanding of Physical Systems for Robot Learning

Not someone, but something: Rethinking trust in the age of medical AI

My Life in Artificial Intelligence: People, anecdotes, and some lessons learnt

SQuat: Subspace-orthogonal KV Cache Quantization

Levels of Analysis for Large Language Models

Narrative Context Protocol: An Open-Source Storytelling Framework for Generative AI

Conceptualizing Uncertainty: A Concept-based Approach to Explaining Uncertainty

Low-Confidence Gold: Refining Low-Confidence Samples for Efficient Instruction Tuning

A calibration test for evaluating set-based epistemic uncertainty representations

Multi-branch of Attention Yields Accurate Results for Tabular Data

PAR-AdvGAN: Improving Adversarial Attack Capability with Progressive Auto-Regression AdvGAN

Latent Swap Joint Diffusion for 2D Long-Form Latent Generation

LIMO: Less is More for Reasoning

Implementing Large Quantum Boltzmann Machines as Generative AI Models for Dataset Balancing

A Survey on Memory-Efficient Transformer-Based Model Training in AI for Science

Breaking Memory Limits: Gradient Wavelet Transform Enhances LLMs Training

Back Home: A Computer Vision Solution to Seashell Identification for Ecological Restoration

DIVE: Taming DINO for Subject-Driven Video Editing

AIM: Adaptive Inference of Multi-Modal LLMs via Token Merging and Pruning

Puzzle Similarity: A Perceptually-guided Cross-Reference Metric for Artifact Detection in 3D Scene Reconstructions

Receding Hamiltonian-Informed Optimal Neural Control and State Estimation for Closed-Loop Dynamical Systems

Fuse Before Transfer: Knowledge Fusion for Heterogeneous Distillation

Recovering Manifold Structure Using Ollivier-Ricci Curvature

Simulated patient systems are intelligent when powered by large language model-based AI agents

GSON: A Group-based Social Navigation Framework with Large Multimodal Model

Task Arithmetic for Language Expansion in Speech Translation

Geometric Algebra Meets Large Language Models: Instruction-Based Transformations of Separate Meshes in 3D, Interactive and Controllable Scenes

Latent Adversarial Training Improves Robustness to Persistent Harmful Behaviors in LLMs

IRASim: A Fine-Grained World Model for Robot Manipulation

MALLM-GAN: Multi-Agent Large Language Model as Generative Adversarial Network for Synthesizing Tabular Data

Long-Term Fairness Inquiries and Pursuits in Machine Learning: A Survey of Notions, Methods, and Challenges

Online Concurrent Multi-Robot Coverage Path Planning

The pitfalls of next-token prediction

Adversarial attacks and defenses in explainable artificial intelligence: A survey

Demystifying Misconceptions in Social Bots Research

A Multi-Agent System Enables Versatile Information Extraction from the Chemical Literature

What Does 'Human-Centred AI' Mean?

Illuminating the Three Dogmas of Reinforcement Learning under Evolutionary Light

Enhancing Student Learning with LLM-Generated Retrieval Practice Questions: An Empirical Study in Data Science Courses

SLR: Automated Synthesis for Scalable Logical Reasoning

Towards Reliable Proof Generation with LLMs: A Neuro-Symbolic Approach

2D-Curri-DPO: Two-Dimensional Curriculum Learning for Direct Preference Optimization

An Algebraic Approach to Moralisation and Triangulation of Probabilistic Graphical Models

SAKE: Steering Activations for Knowledge Editing

Intrinsic Barriers and Practical Pathways for Human-AI Alignment: An Agreement-Based Complexity Analysis

A Scalable Approach to Probabilistic Neuro-Symbolic Robustness Verification

Ensuring Medical AI Safety: Interpretability-Driven Detection and Mitigation of Spurious Model Behavior and Associated Data

Strategist: Self-improvement of LLM Decision Making via Bi-Level Tree Search

A finite time analysis of distributed Q-learning

Foundation Models for Demand Forecasting via Dual-Strategy Ensembling

Supervised Quantum Image Processing

Secure Tug-of-War (SecTOW): Iterative Defense-Attack Training with Reinforcement Learning for Multimodal Model Security

ReXGroundingCT: A 3D Chest CT Dataset for Segmentation of Findings from Free-Text Reports

XAI for Point Cloud Data using Perturbations based on Meaningful Segmentation

Exploring the Stratified Space Structure of an RL Game with the Volume Growth Transform

Bridging Synthetic and Real-World Domains: A Human-in-the-Loop Weakly-Supervised Framework for Industrial Toxic Emission Segmentation

Staining and locking computer vision models without retraining

Teach Me to Trick: Exploring Adversarial Transferability via Knowledge Distillation

ChemDFM-R: An Chemical Reasoner LLM Enhanced with Atomized Chemical Knowledge

Fine-Tuning Code Language Models to Detect Cross-Language Bugs

MapAgent: Trajectory-Constructed Memory-Augmented Planning for Mobile Task Automation

Machine learning-based multimodal prognostic models integrating pathology images and high-throughput omic data for overall survival prediction in cancer: a systematic review

Created by

Haebom

저자

Charlotte Jennings (National Pathology Imaging Cooperative, Leeds Teaching Hospitals NHS Trust, Leeds, UK), Andrew Broad (National Pathology Imaging Cooperative, Leeds Teaching Hospitals NHS Trust, Leeds, UK, University of Leeds, Leeds, UK), Lucy Godson (National Pathology Imaging Cooperative, Leeds Teaching Hospitals NHS Trust, Leeds, UK, University of Leeds, Leeds, UK), Emily Clarke (National Pathology Imaging Cooperative, Leeds Teaching Hospitals NHS Trust, Leeds, UK), David Westhead (University of Leeds, Leeds, UK), Darren Treanor (National Pathology Imaging Cooperative, Leeds Teaching Hospitals NHS Trust, Leeds, UK)

개요

본 연구는 조직병리학 및 분자 데이터를 통합하는 다중 모드 기계 학습을 이용한 암 예후 예측에 대한 체계적 문헌 검토를 수행했습니다. 2024년 12월 8일까지 EMBASE, PubMed 및 Cochrane CENTRAL 데이터베이스를 검색하고, 인용문 분석을 통해 전자 현미경 이미지(WSI)와 고 처리량 오믹스 데이터를 결합하여 전체 생존율을 예측하는 연구들을 선별했습니다. 총 48편의 연구(모두 2017년 이후)가 선정되었으며, 모든 연구는 The Cancer Genome Atlas 데이터를 사용했습니다. 사용된 방법론으로는 정규화 Cox 회귀 분석(4편), 고전적인 기계 학습(13편), 심층 학습(31편)이 포함되었고, 보고된 c-지수는 0.550~0.857 범위였습니다. 다중 모드 모델은 일반적으로 단일 모드 모델보다 성능이 우수했지만, 모든 연구에서 불확실하거나 높은 편향, 제한적인 외부 검증, 임상적 유용성에 대한 부족한 고려 등의 문제점이 나타났습니다.

시사점, 한계점

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시사점: 다중 모드 WSI-오믹스 생존 예측은 빠르게 성장하는 분야이며 유망한 결과를 보여주지만, 향상된 방법론적 엄격성, 더 광범위한 데이터 세트 및 임상 평가가 필요합니다. 다중 모드 모델이 단일 모드 모델보다 성능이 우수하다는 점을 확인했습니다.

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한계점: 모든 연구에서 불확실하거나 높은 편향(bias)이 존재했습니다. 대부분의 연구가 제한적인 외부 검증을 수행했습니다. 임상적 유용성에 대한 고려가 부족했습니다. 모든 연구가 The Cancer Genome Atlas 데이터에 의존했습니다.

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