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ECG-SMART-NET: A Deep Learning Architecture for Precise ECG Diagnosis of Occlusion Myocardial Infarction

Created by
  • Haebom

Author

Nathan T. Riek, Murat Akcakaya, Zeineb Bouzid, Tanmay Gokhale, Stephanie Helman, Karina Kraevsky-Philips, Rui Qi Ji, Ervin Sejdic, Jessica K. Z egre-Hemsey, Christian Martin-Gill, Clifton W. Callaway, Samir Saba, Salah Al-Zaiti

Outline

This paper presents the development and evaluation of ECG-SMART-NET for the identification of occlusive myocardial infarction (OMI). OMI is a severe cardiac arrest characterized by complete occlusion of one or more coronary arteries, requiring immediate cardiac catheterization to restore blood flow to the heart. In 12-lead electrocardiograms (ECGs), two-thirds of OMI cases are visually difficult to identify and can be fatal if not identified quickly. In this study, we propose ECG-SMART-NET, a clinically relevant modification of the existing ResNet-18 architecture designed to capture temporal features and spatial correspondence or mismatch between leads. We compared our results with other state-of-the-art models using a multi-site real clinical dataset (10,393 ECGs, 7,397 patients, OMI incidence 7.2%) and found that ECG-SMART-NET outperformed other models in OMI classification, achieving a test AUC of 0.953 [0.921, 0.978].

Takeaways, Limitations

Takeaways:
ECG-SMART-NET outperforms state-of-the-art random forest models in OMI prediction.
We demonstrate that this architecture is more suitable for OMI identification than the existing ResNet-18 architecture.
We present a novel CNN architecture that effectively learns temporal and spatial features.
It can contribute to improving early diagnosis and treatment of OMI.
Limitations:
Further consideration is needed regarding the size and diversity of the dataset used.
Additional evaluation of generalization performance across diverse populations is needed.
Further research and validation are needed for clinical application.
Further research is needed on the interpretability of the model.
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