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INSIGHT: Explainable Weakly-Supervised Medical Image Analysis

Created by
  • Haebom

Author

Wenbo Zhang, Junyu Chen, Christopher Kanan

Outline

This paper proposes INSIGHT, a novel weakly supervised learning-based aggregator for analyzing large-scale medical images (3D CT scans and electron microscope images). To address the inherent shortcomings of existing methods, such as failure to localize small but important details and reliance on post-visualization techniques, INSIGHT integrates heatmap generation with inductive bias. Starting from pre-trained feature maps, it leverages a detection module with a small convolutional kernel and a context module with a large receptive field to capture fine details and suppress localized false positives. The resulting internal heatmap highlights diagnostically important regions. On CT and WSI benchmarks, INSIGHT achieves state-of-the-art classification performance and high weakly supervised learning-based semantic segmentation performance.

Takeaways, Limitations

Takeaways:
Precise localization of small, critical details in high-volume medical images
Effectively highlight diagnostically important areas without the need for post-visualization techniques.
Achieving state-of-the-art performance on CT and WSI datasets
Excellent performance in semantic segmentation based on weakly supervised learning
Ensure reproducibility and accessibility through open code and websites.
Limitations:
Because it relies on weakly supervised learning, there is a possibility of performance degradation if accurate annotations are lacking.
Performance for certain types of medical imaging may be limited compared to others.
Need to evaluate generalization performance across various medical image types
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