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Tackling Hallucination from Conditional Models for Medical Image Reconstruction with DynamicDPS

Created by
  • Haebom

Author

Seunghoi Kim, Henry FJ Tregidgo, Matteo Figini, Chen Jin, Sarang Joshi, Daniel C. Alexander

Outline

In this paper, we propose DynamicDPS, a novel method to reduce hallucinations (structures that are not present in the real data), which is a serious problem in medical image reconstruction, especially in data-driven conditional models. DynamicDPS is a diffusion-based framework that integrates conditional and unconditional diffusion models to systematically reduce hallucinations while improving low-quality medical images. After an initial reconstruction using the conditional model, it is improved using an adaptive diffusion-based inverse problem solver, and the optimal starting point is selected sample-wise and Wolfe's linear search is applied to improve efficiency and image fidelity. Through extensive evaluations on synthetic and real MR scans, we show that DynamicDPS reduces hallucinations and improves tissue volume estimation by more than 15% while using only 5% of the sampling steps compared to conventional diffusion models. As a model-independent and learning-free method, it provides a powerful solution to hallucination reduction in medical images.

Takeaways, Limitations

Takeaways:
A novel method to effectively address hallucination problems in medical image reconstruction is presented.
Improve the performance of conditional models and improve the accuracy of downstream tasks such as tissue volume estimation.
Significantly improves efficiency by reducing sampling steps compared to existing diffusion models.
Applicable to various conditional models without model dependency.
Increase reproducibility and usability by making your code publicly available.
Limitations:
Currently, only experimental results for MRI images are presented. Generalizability to other medical imaging modalities needs to be verified.
Extensive experiments on different types of conditional models are still lacking.
Wolfe's line search is used, but comparative analysis with other optimization methods may be necessary.
Additional performance validation in actual clinical environments is required.
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