This paper presents a zero-shot domain adaptation method that adapts a model to a target domain without target domain image data. Existing studies have used CLIP's embedding space and text descriptions to mimic target style features, but they have limitations in capturing complex real-world changes and long adaptation times. In this paper, we propose a synthetic image-based domain adaptation (SIDA) method that utilizes synthetic images that provide diverse and detailed style information instead of text descriptions. SIDA generates synthetic images that reflect the target domain style through image transformation based on source images, and effectively models real-world changes using the domain mix and patch style transfer modules. Domain mix expands the representation within a domain by mixing various styles, and patch style transfer assigns different styles to individual patches. Experimental results show that our method achieves state-of-the-art performance in various zero-shot adaptation scenarios and significantly reduces the adaptation time, demonstrating high efficiency.