This paper proposes a knowledge editing technique to address challenges in applying large-scale multimodal models (LMMs) to autonomous driving systems (ADS), such as traffic knowledge errors, complex road environments, and diverse vehicle conditions. We aim to improve the performance of ADS by leveraging knowledge editing, which allows for goal-directed modification of model behavior without requiring full retraining. To this end, we introduce ADS-Edit, a multimodal knowledge editing dataset that encompasses diverse real-world scenarios, multiple data types, and comprehensive evaluation metrics. We then draw several conclusions through extensive experiments. The code and data are publicly available.