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Prompt4Trust: A Reinforcement Learning Prompt Augmentation Framework for Clinically-Aligned Confidence Calibration in Multimodal Large Language Models

Created by
  • Haebom

Author

Anita Kriz, Elizabeth Laura Janes, Xing Shen, Tal Arbel

Outline

To address two challenges hindering the safe application of multimodal large language models (MLLMs) in healthcare—prompt design sensitivity and the generation of incorrect responses with high confidence—we propose Prompt4Trust, a reinforcement learning (RL)-based framework for confidence calibration of MLLMs. Prompt4Trust uses lightweight LLMs to generate auxiliary prompts whose confidence matches the MLLM's predictive accuracy. This method prioritizes confidence calibration in clinical contexts and improves medical image question-answering performance on the PMC-VQA benchmark. Furthermore, Prompt4Trust, trained on a small MLLM, demonstrates zero-shot generalization to larger MLLMs, suggesting the potential for scalable calibration without high computational costs.

Takeaways, Limitations

Takeaways:
Presenting the possibility of improving the reliability and accuracy of MLLM in the medical field.
Improving MLLM reliability in safety-critical environments through automated prompt engineering.
Achieving SOTA and zero-shot generalization on the PMC-VQA benchmark.
Scalability through potential reduction in computational costs.
Limitations:
The specific Limitations is not explicitly mentioned in the paper. (There is no direct mention of Limitations in the abstract.)
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