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EEG-Language Pretraining for Highly Label-Efficient Clinical Phenotyping

Created by
  • Haebom

Author

Sam Gijsen, Kerstin Ritter

Outline

This paper presents the first electroencephalogram-to-language model (ELM) using clinical reports and 15,000 electroencephalogram (EEG) data sets. Given that previous multimodal language modeling research has not been applied to clinical phenotypic analysis of functional brain data, we combine multimodal alignment through time-series trimming and text segmentation, and propose multi-instance learning-based augmentation to mitigate inconsistencies between irrelevant EEG or text segments. Experimental results demonstrate that the proposed multimodal model significantly outperforms EEG-only models across four clinical trials, enabling zero-shot classification and retrieval of both neural signals and reports for the first time. This represents a significant advance demonstrating the clinical applicability of ELM.

Takeaways, Limitations

Takeaways:
We demonstrate improved performance in clinical phenotyping using multimodal learning that combines electroencephalography (EEG) and clinical reports.
Introducing new possibilities for clinical applications through implementation of zero-shot classification and neural signal and report retrieval functions.
Mitigating the mismatch problem between EEG and text segments through multi-instance learning-based scaling.
Performance improvements compared to EEG-only models were verified through four clinical evaluations.
Limitations:
The size of the EEG data used in this paper (15,000 data) may be relatively small compared to large-scale datasets.
The need to more comprehensively consider diverse clinical conditions and patient characteristics.
Further research is needed to determine the model's generalization performance and applicability to other types of EEG data.
More detailed analysis and evaluation of the performance of zero-shot classification is needed.
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