Daily Arxiv

This page organizes papers related to artificial intelligence published around the world.
This page is summarized using Google Gemini and is operated on a non-profit basis.
The copyright of the paper belongs to the author and the relevant institution. When sharing, simply cite the source.

A Brain-to-Population Graph Learning Framework for Diagnosing Brain Disorders

Created by
  • Haebom

Author

Qianqian Liao, Wuque Cai, Hongze Sun, Dongze Liu, Duo Chen, Dezhong Yao, Daqing Guo

Outline

This paper addresses the problem that graph-based methods developed for brain disease diagnosis using functional connectivity rely on existing brain atlases and overlook the mixing effects of rich information within the atlas and site- and phenotypic variability. To this end, we propose a two-stage Brain-to-Population Graph Learning (B2P-GL) framework that integrates semantic similarity of brain regions with state-based population graph modeling. In the first stage, we enrich the graph representation by leveraging brain atlas knowledge from GPT-4 and refine the brain graph using an adaptive node reassignment graph attention network. In the second stage, we integrate phenotypic data into the population graph construction and feature fusion to mitigate mixing effects and improve diagnostic performance. Experimental results on the ABIDE I, ADHD-200, and Rest-meta-MDD datasets demonstrate that B2P-GL outperforms state-of-the-art methods in predictive accuracy and enhances interpretability.

Takeaways, Limitations

Takeaways:
Enhancing Brain Atlas Knowledge-Based Graph Representation Using GPT-4
Improving Brain Graphs with Adaptive Node Reassignment Graph Attention Networks
Population graph construction and feature fusion using phenotypic data
Achieving state-of-the-art performance on ABIDE I, ADHD-200, and Rest-meta-MDD datasets.
Improved diagnostic accuracy and increased interpretability
Providing a reliable and personalized approach to diagnosing brain disorders.
Increased clinical applicability
Limitations:
Specific Limitations is not specified in the paper (e.g., characteristics of the dataset, generalization performance of the model, etc.).
👍