Check out our newly launched website!
Go to homepage
GY (Glucagon Yellow) [Catalog # P024]
■ Chemical structure & Information
Glucagon yellow is a pancreatic alpha cell selective probe over beta cell. Glucagon yellow showed dose dependent fluorescence increase upon treatment of glucagon with slight red shift. In pancreatic tissue, Glucagon yellow showed a good correlation with glucagon antibody, but low correlation with insulin antibody
■ Cell Image
Fluorescence colocalization images of Glucagon Yellow in pancreas tissue. Fluorescence microscope images of Glucagon Yellow (a: TRITC channel), glucagon antibody (b: Cy5 channel), insulin antibody (f: Cy5 channel) and merged images (c for a plus b, g for e plus f). Colocalization scatter plot (d: Pearson’s coefficient 0.950, h: Pearson’s coefficient 0.681). Scale bar 20 µm.
■ Related probes: TP-alpha
■ Known Property
pancreatic alpha cell
■ Application
Immunofluorescence
■ Cell selectivity mechanism
POLD (glucagon)
pancreatic alpha cell
■ Application
Immunofluorescence
■ Cell selectivity mechanism
POLD (glucagon)
■ Reference
1.
Synthesis of a bodipy library and its application to the development of live cell glucagon imaging probe, Lee, J. S.; Kang, N. Y.; Kim, Y. K.; Samanta, A.; Feng, S.; Kim, H. K.; Vendrell, M.; Park, J. H.; Chang, Y. T.* J. Am. Chem. Soc. 2009, 131, 10077-10082.\
■ ORDER
International
USD 350 + VAT (10%) + Fedex delivery charge
In Korea
KRW 450,000 + VAT (10%)
100 nmol (dried form: equivalent to 1 mM / 100 µL)
■ Storage
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C
■ General Use Guide
•
More than 1/100 dilution of 10mM of DMSO stock solution is essential
•
For biomedical use to avoid DMSO concentration higher than 1%.
•
Working concentrations for specific applications should be determined by the investigator.
•
It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
precipitated out from buffer solution.
precipitated out from buffer solution.
■ Data sheet PDf file
Glucagon Yellow data sheet v0.2.pdf364.99KB