# PiY [Catalog # P025]

**■ Chemical structure & Information**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/223638_FbmAa6BFn2LT9r3Ogu?q=80&s=1280x180&t=outside&f=webp)

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/223703_EgQQZUhSbKCQz36jO5?q=80&s=1280x180&t=outside&f=webp)

**PiY** (Pancreatic islet Yellow) is a pancreatic beta cell selective probe over alpha cell or acinar cell. Through i.v. injection of PiY into mouse tale vein, pancreatic islet was vividly visualized to facilitate the islet isolation

**■ Cell Image**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/223725_saBjzUe2YmuRNI9Avv?q=80&s=1280x180&t=outside&f=webp)

3D structure processed image of a pancreatic islet. The fluorescent images of PiY(red) and FITC-dextran (green) were taken using TRITC and FITC channels, respectively. DAPI(blue) stain shows nuclei. Scale bar=50mm

■ **Related probes**: TP-beta, PiF

■ **Known Property**
pancreatic beta cell probe
■ **Application**
Immunofluorescence and visualization of islets in pancreatic tissue by i.v. injection of mouse
■ **Cell selectivity mechanism**
Unknown

■ **Reference**

1. **Visualization and isolation of Langerhans islets by fluorescent probe PiY**, Kang, N. Y.; Lee, S. C.; Park, S. J.; Ha, H. H.; Yun, S. W.; Kostromina, E.; Gustavsson, N.; Ali, Y.; Chandran, Y.; Chun, H. S.; Bae, M. A.; Ahn, J. H.; Han, W.; Radda, G. K.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2013, 52, 8557-8560.

■ **ORDER**

**International**

**USD 350 + VAT (10%) + Fedex delivery charge**

**In Korea**

**KRW 450,000 + VAT (10%)**

**100 nmol** (dried form: equivalent to 1 mM / 100 µL)

[order@senprobe.com](mailto:order@senprobe.com)

■ **Storage**
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

■ **General Use Guide**

- More than 1/100 dilution of 10mM of DMSO stock solution is essential

-  For biomedical use to avoid DMSO concentration higher than 1%.

- Working concentrations for specific applications should be determined by the investigator.

- It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
- precipitated out from buffer solution.

■ **Data sheet PDF file**

PiY data sheet v0.2.pdf

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