# MTX [Catalog # P043]

**■ Chemical structure & Information**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/215620_3Ys0Af89UhxWvaYt7f?q=80&s=1280x180&t=outside&f=webp)

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/215643_fITyF1jAGUkV6HYcPL?q=80&s=1280x180&t=outside&f=webp)

**MTX**, a modified version of MTY have been developed for assessing the temperature of mitochondria in living cells. 
Their use as nanothermometers is dependent on their long term retention in mitochondria, lack of interference with mitochondrial activities, and on their propensity to be unaffected by fluctuations of membrane potential, which is likely enabled by their binding to specific targets within mitochondria.

**■ Cell Image**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/215728_AugUQ4ySbDreFI7SkI?q=80&s=1280x180&t=outside&f=webp)

Spectral properties of the **MTX **probe. (a) fluorescence excitation (red) and emission (green) spectra of MTX (1.5 µM) H2O at 32 ◦C and 52 ◦C; (b) fluorescence response of MTX in solution to temperature (% of fluorescence at 32 ◦C). The probe was incubated for 10, 30, and 60 min at 32 ◦C followed by 10, 30, 60 min incubation at 52 ◦C, and the temperature was decreased back to 32 ◦C, as indicated. n = 3; values are means ± SD;

■ **Related probes: **ER ThermAC

■ **Known Property**

Temperature Probe
■ **Application**

Cell organelle imaging
■ **Cell selectivity mechanism**
unknown

■ **Reference**

1. **Pitfalls in Monitoring Mitochondrial Temperature Using Charged Thermosensitive Fluorophores**, Chrétien, D.; Bénit, P.; Leroy, C.; El-Khoury, R.; Park, S.; Lee, J. Y.; Chang, Y. T.; Lenaers, G.; Rustin, R.; Rak, M. Chemosensors 2020, 8, 124.

■ **ORDER**

**International**

**USD 350 + VAT (10%) + Fedex delivery charge**

**In Korea**

**KRW 450,000 + VAT (10%)**

**100 nmol** (dried form: equivalent to 1 mM / 100 µL)

[order@senprobe.com](mailto:order@senprobe.com)

■ **Storage**
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

■ **General Use Guide**

- More than 1/100 dilution of 10mM of DMSO stock solution is essential

-  For biomedical use to avoid DMSO concentration higher than 1%.

- Working concentrations for specific applications should be determined by the investigator.

- It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
- precipitated out from buffer solution.

■** Data sheet PDF file**

MTX data sheet v0.2.pdf

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