# E144 [Catalog # P022]

**■ Chemical structure & Information**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/220616_fmkxxIvqjlORIQSxmx?q=80&s=1280x180&t=outside&f=webp)

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/220628_ocP58pqzrJ4yYg7BIk?q=80&s=1280x180&t=outside&f=webp)

**E144** is a selective RNA probe over DNA. E144 was disclosed through in vitro DNA/RNA selectivity screening and live cell staining for nucleolus

**■ Cell Image**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/220650_mIO6YIb2Tu7J0LS8tS?q=80&s=1280x180&t=outside&f=webp)

Live Cell RNA Staining with Selected Dyes E36, **E144**, and F22 were tested at a 5 mM concentration. The picture of F22-stained 3T3 cells was obtained in a 1 mM dye concentration.
1000x magnification was utilized in the imaging. The scale bar represents 5 mm. Image brightness and contrast were slightly adjusted to improve picture quality. E36,** E144** (green: FITC channel), and F22 (red: Cy3 channel) are shown.

■** Related probes**: E36, F22

■ **Known Property**
RNA probe
■ **Application**
Selective fluorescent imaging of nuclear structure in live cells
■ **Cell selectivity mechanism**
RNA

■ **Reference**

1. **RNA-selective, live cell imaging probes for studying nuclear structure and function.**, Li, Q., Kim, Y. K., Namm, J., Kulkarni, A., Rosania, G., Ahn, Y. H., Chang, Y. T.* Chem. Biol. 2006, 13, 615-623.

2. **A protocol for preparing, characterizing and using three RNA-specific, live cell imaging probes: E36**, E144 and F22 Li, Q.; Chang, Y. T.* Nat. Protoc. 2006, 1, 2922-2932.

■ **ORDER**

**International**

**USD 350 + VAT (10%) + Fedex delivery charge**

**In Korea**

**KRW 450,000 + VAT (10%)**

**100 nmol** (dried form: equivalent to 1 mM / 100 µL)

[order@senprobe.com](mailto:order@senprobe.com)

■ **Storage**
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

■ **General Use Guide**

- More than 1/100 dilution of 10mM of DMSO stock solution is essential

-  For biomedical use to avoid DMSO concentration higher than 1%.

- Working concentrations for specific applications should be determined by the investigator.

- It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
- precipitated out from buffer solution.

■ **Data sheet PDF file**

E144 data sheet v0.2.pdf

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