# cLG (cancerous Liver Green) [Catalog #P058]

**■ Chemical structure & Information**

![Image](https://upload.cafenono.com/image/slashpagePost/20250428/155654_1yr3SZrWMESu7iJKkR?q=80&s=1280x180&t=outside&f=webp)

![Image](https://upload.cafenono.com/image/slashpagePost/20250428/192056_WUBrBvEV4NjuUJ4IfS?q=80&s=1280x180&t=outside&f=webp)

**cLG** was selective for liver cancer cells, whereas hLR was selective for healthy liver cells. These two probes selectively stained the targeted cells in the liver section, which was confirmed by H&E and antibody staining. In addition, the use of a cocktail of these two probes provided high contrast between the cancerous region and the normal region, enabling accurate cancer imaging. 

**■ Image**

![Image](https://upload.cafenono.com/image/slashpagePost/20250428/154331_hnVBt0PSLh4sVSDTw7?q=80&s=1280x180&t=outside&f=webp)

Cancer cell recognition in cancerous liver tissue using **cLG**. (a) Liver tissue imaging of **cLG**. The liver tissues were incubated with **cLG** (5 μM) for 30 min. (b) H&E staining of the liver tissues. (c) Colocalization of anti-GPC and** cLG** in the liver tissue. Concordant results were obtained from three independent experiments.

![Image](https://upload.cafenono.com/image/slashpagePost/20250428/154748_HOAtn1K8IAIorti69B?q=80&s=1280x180&t=outside&f=webp)

Costaining of **cLG** and hLR in cancerous liver tissue. The cocktail was made with hLR (10 μM) and **cLG** (5 μM). The tissue section was incubated with cocktail for 30 min. Tissue thickness is 15 μm. Concordant results were obtained from three independent experiments.

■ **Related probes**: **hLR**

■ **Known Property**
liver cancer cell selective probe
■ **Application**
fluorescence image
■ **Cell selectivity mechanism**
GOLD (SLC27A2)

■ **Reference**

1. **A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging**, Gao M, Lee SH, Kwon HY, Ciaramicoli LM, Jo E, Yu YH, Li F, Kim B, Hong K, Lee JS, Kim N, Oh Y, Im CY, Tan CSH, Ha HH, Chang YT., ACS Cent Sci., 2024 Dec 16;11(1):76-83. 

■ **ORDER**

**International**

**USD 350 + VAT (10%) + Fedex delivery charge**

**In Korea**

**KRW 450,000 + VAT (10%)**

**100 nmol** (dried form: equivalent to 1 mM / 100 µL)

[order@senprobe.com](mailto:order@senprobe.com)

■ **Storage**
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

■ **General Use Guide**

- More than 1/100 dilution of 10mM of DMSO stock solution is essential

-  For biomedical use to avoid DMSO concentration higher than 1%.

- Working concentrations for specific applications should be determined by the investigator.

- It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
- precipitated out from buffer solution.

■ **Data sheet PDF file**

cLG data sheet.pdf

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