NeutropG [Catalog # P055]

Mon, 20 Jan 2025 11:19:40 GMT

**■ Chemical structure & Information**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/223010_elW86iOn0R0Ytk7aVj?q=80&s=1280x180&t=outside&f=webp)

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/223023_df7TVCXEUQvXENxudY?q=80&s=1280x180&t=outside&f=webp)

**NeutropG** is a selective fluorescent probe for identifying and imaging live neutrophils, showing high specificity among granulocytes. It targets lipid droplet biosynthesis enzymes (ACSL and DGAT) following the Metabolism-Oriented Live-cell Distinction (MOLD) concept. NeutropG is fast, stable, wash-free, and biocompatible, proving effective in clinical blood samples and demonstrating potential as a diagnostic tool for metabolically active neutrophils

**■ Cell Image**

![Image](https://upload.cafenono.com/image/slashpagePost/20250206/223046_Tq0IniFvbw3ijbMl4J?q=80&s=1280x180&t=outside&f=webp)

Fluorescence images showed the intracellular fluorescent intensity of neutrophils, eosinophils and basophils after treatment with NeutropG (0.2 μM), Nile Red (1 nM) and Hoechst (1 μg mL−1) for 1 h, 30 min and 10 min, respectively. The specific antibody for each cell type was added to cells and incubated for 30 min prior to imaging.

■ **Known Property**
Neutrophil probe
■ **Application**
Immunofluorescence
■ **Cell selectivity mechanism**
MOLD

■ **Reference**

1. **Neutrophil Selective Fluorescent Probe Development through Metabolism-Oriented Live-cell Distinction**, Gao, M.; Lee, S. H.; Park, S. H.; Ciaramicoli, L. M.; Kwon, H. Y.; Cho, H.; Jeong, J.; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. 2021, 60, 23742-23749.

■ **ORDER**

**International**

**USD 350 + VAT (10%) + Fedex delivery charge**

**In Korea**

**KRW 450,000 + VAT (10%)**

**100 nmol** (dried form: equivalent to 1 mM / 100 µL)

[order@senprobe.com](mailto:order@senprobe.com)

■ **Storage**
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

■ **General Use Guide**

- More than 1/100 dilution of 10mM of DMSO stock solution is essential

- For biomedical use to avoid DMSO concentration higher than 1%.

- Working concentrations for specific applications should be determined by the investigator.

- It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
- precipitated out from buffer solution.

■ **Data sheet PDF file**

NeutropG data sheet v0.2.pdf