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Beta-cell probes

PiY [Catalog # P025]
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🔬PHOENIX FLUOR

PiY [Catalog # P025]

■ Chemical structure & Information
PiY (Pancreatic islet Yellow) is a pancreatic beta cell selective probe over alpha cell or acinar cell. Through i.v. injection of PiY into mouse tale vein, pancreatic islet was vividly visualized to facilitate the islet isolation
■ Cell Image
3D structure processed image of a pancreatic islet. The fluorescent images of PiY(red) and FITC-dextran (green) were taken using TRITC and FITC channels, respectively. DAPI(blue) stain shows nuclei. Scale bar=50mm
Related probes: TP-beta, PiF
Known Property
pancreatic beta cell probe
Application
Immunofluorescence and visualization of islets in pancreatic tissue by i.v. injection of mouse
Cell selectivity mechanism
Unknown
Reference
1.
Visualization and isolation of Langerhans islets by fluorescent probe PiY, Kang, N. Y.; Lee, S. C.; Park, S. J.; Ha, H. H.; Yun, S. W.; Kostromina, E.; Gustavsson, N.; Ali, Y.; Chandran, Y.; Chun, H. S.; Bae, M. A.; Ahn, J. H.; Han, W.; Radda, G. K.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2013, 52, 8557-8560.

ORDER
International
USD 350 + VAT (10%) + Fedex delivery charge
In Korea
KRW 450,000 + VAT (10%)
100 nmol (dried form: equvalent to 1 mM / 100 µL)

Storage
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

General Use Guide
More than 1/100 dilution of 10mM of DMSO stock solution is essential
For biomedical use to avoid DMSO concentration higher than 1%.
Working concentrations for specific applications should be determined by the investigator.
It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
precipitated out from buffer solution.
Data sheet PDF file
PiY data sheet v0.2.pdf689KB
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