# CyB C9 [Catalog # P050]

**■ Chemical structure & Information**

![Image](https://upload.cafenono.com/image/slashpagePost/20250919/100804_8zk2tZeIoNH2c5avfn?q=80&s=1280x180&t=outside&f=webp)

![Image](https://upload.cafenono.com/image/slashpagePost/20250207/131533_JRB1HzdiMfE6irRH4C?q=80&s=1280x180&t=outside&f=webp)

**CyB C9** has a rapid process time (2 h), is nontoxic, and more sensitive in detecting senescent MSCs both in early and in late stages.

**■ Cell Image**

![Image](https://upload.cafenono.com/image/slashpagePost/20250207/131600_4QnFKhHGLABeH7xb7D?q=80&s=1280x180&t=outside&f=webp)

A. Positive  staining  of  **CyB C9** on  senescent  (p25)heMSCs.In comparison, proliferative (p8) heMSCs show the absence of staining. B. The localization of CyBC9stain in senescent (p25) heMSCs. A) Costaining of heMSCs with CyB C9 and MitoTracker Green. Scale bar:10μm. A graph representing values of the Pearson correlation coefficient of CyBC9costaining with other organelle stains. High Pearson correlation coefficient indicates high localization in the cell organelle. C. Costaining of CyB C9 and SA‐β‐Gal for proliferative (p8) heMSCs treated and not treated with H2O2.Scale bar:100μm. Arrows indicate that cells with positive SA‐β‐gal staining also stain positive for CyB C9.

■ **Known Property**
Senescent Mesenchymal Stromal Cells
selective probe
■ **Application**
Immunofluorescence
■ **Cell selectivity mechanism**
unknown

■ **Reference**

1. **Rapid detection of senescent mesenchymal stromal cells by a fluorescent probe**, Ang, J.; Lee, Y. A.; Raghothaman, D.; Jayaraman, P.; Teo, K. L.; Khan, F. J.; Reuveny, S.; Chang, Y. T.; Kang, N. Y._; Oh, S._ Biotechnol. J. 2019, 1800691.

■ **ORDER**

**International**

**USD 350 + VAT (10%) + Fedex delivery charge**

**In Korea**

**KRW 450,000 + VAT (10%)**

**100 nmol** (dried form: equivalent to 1 mM / 100 µL)

[order@senprobe.com](mailto:order@senprobe.com)

■ **Storage**
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C

■ **General Use Guide**

- More than 1/100 dilution of 10mM of DMSO stock solution is essential

-  For biomedical use to avoid DMSO concentration higher than 1%.

- Working concentrations for specific applications should be determined by the investigator.

- It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
- precipitated out from buffer solution.

■ **Data sheet PDF file**

CyB C9 data sheet v0.2.pdf

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