SUMMARY: A meta-analysis investigates the relationship between dietary protein intake and chronic kidney disease risk, revealing uncertain associations. KEY FINDINGS: Dietary protein intake may influence the progression of chronic kidney disease (CKD). The exact relationship between protein intake and CKD incidence is unclear. Total protein intake is a focus of the meta-analysis. Distinctions are made between plant and animal protein sources. The study is the first meta-analysis on this topic. Correlations among different protein types and CKD risk are explored. Findings may guide dietary recommendations for CKD patients. Further research is needed to clarify these associations. Protein consumption patterns could impact kidney health. The analysis contributes to understanding dietary influences on CKD. CONCLUSION: Dietary protein type may affect chronic kidney disease risk. Uncertainty remains regarding protein intake and CKD incidence. The meta-analysis provides foundational insights for future studies. Distinguishing between plant and animal protein is crucial. Findings could inform dietary guidelines for kidney health.

SUMMARY: Conventional obesity treatments often fail due to biological responses; a carbohydrate-insulin model suggests alternative dietary strategies for effective weight management. KEY FINDINGS: Conventional obesity treatment relies on calorie restriction and increased physical activity. Long-term weight loss success is rare with traditional methods. Calorie restriction triggers biological responses that hinder weight loss. The carbohydrate-insulin model suggests high carbs lead to fat storage. Increased insulin levels promote hunger and reduce metabolic rate. Energy partitioning shifts towards fat storage with high carbohydrate intake. Common obesity forms result from gradual weight gain through this mechanism. Low-fat diets may not address the root causes of obesity. Lowering insulin secretion could enhance weight management effectiveness. The article is part of a broader discussion on obesity causes. CONCLUSION: Traditional weight loss methods often fail due to biological counter-responses. A high-carbohydrate diet can lead to increased fat storage. Understanding insulin's role is crucial for effective weight management. Alternative dietary strategies may improve long-term obesity outcomes. Addressing underlying causes of obesity is essential for sustainable health. KEYWORDS: obesity, weight loss, insulin, carbohydrates, dietary strategies, metabolism, health, energy balance, chronic disease, nutrition