To overcome the limitations of existing passive Large Language Model (LLM)-based agents, this paper proposes AppAgent-Pro, a predictive GUI agent system that actively integrates multi-domain information based on user commands. AppAgent-Pro anticipates users' potential needs and performs in-depth multi-domain information mining to enable more comprehensive and intelligent information acquisition. This has the potential to fundamentally change how we acquire information in our daily lives and significantly impact human society. The code and demo are available on GitHub and through a link to a demo video.