This chapter systematically presents the emerging interdisciplinary field of Human-AI Interaction (HAII) from a Human-Centered AI (HCAI) perspective. It introduces the Human-Centered HAII (HC-HAII) framework, emphasizing the importance of a human-centered approach, rather than a technology-centered one, placing humans at the center of HAII research and applications. The HC-HAII methodology presents human-centered methods, processes, interdisciplinary teams, and a multi-level design paradigm, highlighting key research challenges and future directions. This chapter provides the basic framework for this book, laying the foundation for subsequent chapters and integrating contributions from interdisciplinary researchers and practitioners to advance the theory, methodology, and application of HCAI across diverse HAII fields.