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MoE-Health: A Mixture of Experts Framework for Robust Multimodal Healthcare Prediction

Created by
  • Haebom

Author

Xiaoyang Wang, Christopher C. Yang

Outline

MoE-Health is a novel Mixture of Experts framework for healthcare prediction. It utilizes medical data from various modalities, including electronic health records (EHRs), clinical notes, and medical images, to perform clinical predictions. Unlike existing methods that require complete modality data or rely on manual selection strategies, MoE-Health is designed to handle real-world samples with diverse or incomplete modality data. It flexibly adapts to diverse data availability scenarios by dynamically selecting and combining relevant experts based on available data modalities, leveraging a specialized expert network and a dynamic gating mechanism. It was evaluated on the MIMIC-IV dataset for three clinical prediction tasks: in-hospital mortality prediction, long-term hospitalization prediction, and readmission prediction, and achieved superior performance compared to existing multi-modality fusion methods.

Takeaways, Limitations

Takeaways:
We present a multi-modality fusion framework that effectively processes diverse and incomplete medical data.
It demonstrates superior predictive performance over existing methods and robustness to diverse data availability.
It has high applicability in real medical environments.
Provides flexible adaptability to differences in availability of data from various modalities.
Limitations:
Since it was evaluated using only one MIMIC-IV dataset, generalization performance on other datasets requires further study.
Because the model may be optimized for a specific medical dataset, it may have poor performance when applied to other datasets or clinical tasks.
Further research may be needed to explore the interpretability of MoE-Health's dynamic gating mechanism.
Additional validation and extension studies are needed for application in real clinical settings.
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