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SRMA-Mamba: Spatial Reverse Mamba Attention Network for Pathological Liver Segmentation in MRI Volumes

Created by
  • Haebom

Author

Jun Zeng, Yannan Huang, Elif Keles, Halil Ertugrul Aktas, Gorkem Durak, Nikhil Kumar Tomar, Quoc-Huy Trinh, Deepak Ranjan Nayak, Ulas Bagci, Debesh Jha

Outline

This paper presents SRMA-Mamba, a novel Mamba-based network for early diagnosis and intervention of liver cirrhosis, which plays a crucial role in the prognosis of chronic liver disease. SRMA-Mamba leverages spatial anatomical details from MRI data to model spatial relationships within cirrhotic tissue. By incorporating the Spatial Anatomy-Based Mamba module (SABMamba), we combine sagittal, coronal, and axial anatomical information to construct a global spatial contextual representation, enabling efficient volumetric segmentation of pathological liver structures. Furthermore, we introduce the Spatial Backward Attention Module (SRMA), designed to progressively enhance cirrhotic details in the segmentation map by leveraging a coarse segmentation map and hierarchical encoding features. Experimental results demonstrate that SRMA-Mamba outperforms state-of-the-art methods in 3D pathological liver segmentation. The source code is publicly available.

Takeaways, Limitations

Takeaways:
We effectively utilized the spatial anatomical information of MRI data to improve the accuracy of diagnosing liver cirrhosis.
We achieved superior 3D pathological liver segmentation performance compared to existing methods.
Open source code facilitates reproducibility and further research.
Limitations:
Further research is needed to determine the generalizability of the proposed method (e.g., across different MRI scanners, different types of cirrhosis, etc.).
Validation through large datasets is required.
Further validation is needed for clinical application.
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